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IL-17A Antibody [17B7] (PE)

ArtNr PRS-77-007-0.05mg
Hersteller ProSci
Menge 0.05 mg
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen FC
Clon 17B7
Specific against Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rat
Isotype IgG2a Kappa
Konjugat/Tag PE
NCBI Il17a
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Il17,Ctla8,IL-17,Ctla-8,IL-17A,Il17a
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Primary Antibodies
Manufacturer - Isotype
Rat IgG2a, kappa
Shipping Temperature
Blue Ice
Storage Conditions
The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.
Manufacturer - Research Area
Immunology, Chemokines & Cytokines, Growth Factors
Background
The 17B7 monoclonal antibody specifically binds to mouse and rat IL-17A, a pro-inflammatory cytokine. It is produced by T helper 17 (Th17) cells, a unique subset of IL-23 dependent CD4+ T cells. Interleukin-17A is highly expressed in transplant rejection, asthma, psoriasis, and multiple sclerosis, and enhances the expression of ICAM-1 in human fibroblasts. The homodimer is expressed by activated peripheral CD4+ T lymphocytes. The Interleukin-17A binds to the IL-17 receptors (IL-17R) expressed by mast cells, monocytes and macrophages, fibroblasts, and endothelial and epithelial cells.
By Type
Immunology, Chemokines & Cytokines, Growth Factors
Modifications
None
Purification
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Concentration
batch dependent
Buffer
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Manufacturer - Specificity
The 17B7 monoclonal antibody specifically binds to mouse and rat IL-17A, a pro-inflammatory cytokine.
Clonality
Monoclonal
NCBI Official Name
interleukin 17A
NCBI Organism
Mus musculus; Rattus norvegicus
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note
Optimal dilutions for each application to be determined by the researcher.

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0.05 mg
Lieferbar: In stock
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