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AMPKa1 (Ab 487) Antibody

ArtNr PRS-79-330-0.1mg
Hersteller ProSci
Menge 0.1 mg
Kategorie
Typ Antibody Primary
Format Liquid
Applikationen WB, IHC
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Konjugat/Tag Unconjugated
Citations Kim JE, et al. (2005) J Proteome Res. 4 (4): 1339-1346. Woods A, et al. (2003) J Biol Chem. 278 (31): 28434-28442.
NCBI PRKAA1
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias AMPK,AMPKa1,MACS,PRKCSL,AAPK1,AMPK alpha-1 chain,AMPK-alpha1,HMG-CoA redustase kinase,PRKAA1
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Primary Antibodies
Shipping Temperature
Blue Ice
Storage Conditions
Store antibody at -20˚ C for up to one year.
Molecular Weight
63 kDa
Manufacturer - Research Area
Other
Background
Responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. It also regulates cholesterol synthesis via phosphorylation and inactivation of hormone-sensitive lipase and hydroxymethylglutaryl-CoA reductase. Appears to act as a metabolic stress-sensing protein kinase switching off biosynthetic pathways when cellular ATP levels are depleted and when 5'-AMP rises in response to fuel limitation and/or hypoxia. This is a catalytic subunit.
By Type
Other
Modifications
None
Protein Gi #
94557301
Purification
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Application Note
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Manufacturer - Specificity
This antibody detects endogenous level of total AMPKα 1 protein.
Immunogen
AMPKa1 (Ab-487) antibody was raised in was raised against a peptide sequence around aa.485~489 (S-G-S-V-S) derived from Human AMPKα 1.
Clonality
Polyclonal
NCBI Official Name
protein kinase, AMP-activated, alpha 1 catalytic subunit
NCBI Organism
Homo sapiens
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0.1 mg
Lieferbar: In stock
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