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Cyclin E1 (phospho Thr395) Antibody

ArtNr PRS-79-510-0.1mg
Hersteller ProSci
Menge 0.1 mg
Kategorie
Typ Antibody Primary
Format Liquid
Applikationen WB
Specific against Human (Homo sapiens)
Host Rabbit
Konjugat/Tag Unconjugated
Citations Won K. A., Reed S. I. EMBO J. 15:4182-4193 (1996) Welcker M., Singer J., Loeb K. R., Grim J., Bloecher A., Mol. Cell 12:381-392 (2003)
NCBI CCNE1
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias CCNE,SIGLEC2,CCNE,CCNE1
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Primary Antibodies
Shipping Temperature
Blue Ice
Storage Conditions
Store antibody at -20˚ C for up to one year.
Molecular Weight
48 kDa
Manufacturer - Research Area
Phospho-Specific, Cell Cycle
Background
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition.
By Type
Phospho-Specific, Cell Cycle
Modifications
Phospho-Specific
Protein Gi #
17318559
Purification
Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Application Note
Western Blot: 1:1000
Manufacturer - Specificity
This antibody detects endogenous level of Cyclin E1 only when phosphorylated at threonine 395.
Immunogen
Cyclin E1 (phospho-Thr395) antibody was raised against a peptide sequence around phosphorylation site of threonine 395 (L-L-T (p) -P-P) derived from Human Cyclin E1.
Clonality
Polyclonal
NCBI Official Name
cyclin E1
NCBI Organism
Homo sapiens
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0.1 mg
Lieferbar: In stock
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