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DNA PKcs (Ab 2609) Antibody

ArtNr PRS-79-568-0.1mg
Hersteller ProSci
Menge 0.1 mg
Kategorie
Typ Antibody Primary
Format Liquid
Applikationen WB
Specific against Human (Homo sapiens)
Host Rabbit
Konjugat/Tag Unconjugated
Citations Chan DW, et al. (2002) Genes Dev. Sep 15; 16 (18): 2333-2338Ding Q, et al. (2003) Mol Cell Biol. Aug; 23 (16): 5836-5848Douglas P, et al. (2002) Biochem J. Nov 15; 368 (Pt 1): 243-251
NCBI PRKDC
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias HYRC,p350,DNAPK,DNPK1,HYRC1,XRCC7,DNA-PKcs,EPLG5,HTKL,LERK5,PRKD,PRKDC,P460
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Primary Antibodies
Shipping Temperature
Blue Ice
Storage Conditions
Store antibody at -20˚ C for up to one year.
Molecular Weight
450 kDa
Manufacturer - Research Area
Cell Cycle
Background
The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku (MIM 152690), which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity; PRKDC must be bound to DNA to express its catalytic properties
By Type
Cell Cycle
Modifications
None
Protein Gi #
126032350
Purification
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Application Note
Western Blot: 1:500~1:1000
Manufacturer - Specificity
This antibody detects endogenous level of total DNA PKcs protein.
Immunogen
DNA PKcs (Ab-2609) antibody was raised against a peptide sequence around aa.2607~2611 (V-E-T-Q-A) derived from Human DNA-PK.
Clonality
Polyclonal
NCBI Official Name
protein kinase, DNA-activated, catalytic polypeptide
NCBI Organism
Homo sapiens
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0.1 mg
Lieferbar: In stock
lieferbar

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