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Caspase 9 Antibody

ArtNr PRS-79-643-0.1mg
Hersteller ProSci
Menge 0.1 mg
Kategorie
Typ Antibody Primary
Format Liquid
Applikationen WB
Specific against Human (Homo sapiens)
Host Rabbit
Konjugat/Tag Unconjugated
Citations Zou, H. et al. (1999) J. Biol. Chem. 274, 11549-11556. Deveraux, Q. L. et al. (1998) EMBO J. 17, 2215-2223. Li, P. et al. (1997) Cell 91, 479-489.
NCBI CASP9
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias MCH6,APAF3,APAF-3,PPP1R56,ICE-LAP6,DXS423E,KIAA0178,SB1.8,SMC1,SMC1L1,ICE-like apoptotic protease 6
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Primary Antibodies
Shipping Temperature
Blue Ice
Storage Conditions
Store antibody at -20˚ C for up to one year.
Molecular Weight
47, 37, 35 kDa
Manufacturer - Research Area
Apoptosis, Cancer
Background
Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
By Type
Apoptosis, Cancer
Modifications
None
Protein Gi #
14790124
Purification
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Application Note
Western Blot: 1:1000
Manufacturer - Specificity
This antibody detects endogenous level of total Caspase 9 protein.
Immunogen
Caspase 9 antibody was raised against a peptide sequence around aa.301~305 (T-S-P-E-D) derived from Caspase 9.
Clonality
Polyclonal
NCBI Official Name
caspase 9, apoptosis-related cysteine peptidase
NCBI Organism
This antibody was raised against a peptide sequence around aa.301~305 (T-S-P-E-D) derived from Caspase 9
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0.1 mg
Lieferbar: In stock
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