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Caspase 9 (phospho Thr125) Antibody

Caspase 9 (phospho Thr125) Antibody

ArtNr	PRS-79-781-0.1mg
Hersteller	ProSci
Menge	0.1 mg
Kategorie	Neuroscience Neural Epigenetics Antibodies Cell Biology Cell Status Apoptosis Immunohistochemistry Western Blot Primary Antibodies
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
Citations	Duan H., J. Biol. Chem. 271:16720-16724(1996). Srinivasula S.M., J. Biol. Chem. 271:27099-27106(1996). Hadano S., Mamm. Genome 10:757-760(1999)
NCBI	CASP9
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	APAF-3,MCH6,RNCASP9,CASP-9,ICE-LAP6
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Store antibody at -20˚ C for up to one year.
Molecular Weight	47 kDa
Manufacturer - Research Area	Phospho-Specific
Background	Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
By Type	Phospho-Specific
Modifications	Phospho-Specific
Protein Gi #	14790124
Purification	Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Concentration	1 mg/mL
Buffer	Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Application Note	Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Manufacturer - Specificity	The antiserum was produced against synthesized phosphopeptide derived from human Caspase 9 around the phosphorylation site of threonine 125 (P-E-TP-P-R).
Immunogen	Caspase 9 (phospho Thr125) antibody was raised against a peptide sequence around phosphorylation site of threonine 125 (P-E-T (p)-P-R) derived from Human Caspase 9.
Clonality	Polyclonal
NCBI Official Name	caspase 9, apoptosis-related cysteine peptidase
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 0.1 mg

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Lieferung vsl. bis 01.01.2026

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