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CDK5 (phospho Tyr15) Antibody

ArtNr PRS-79-970-0.1mg
Hersteller ProSci
Menge 0.1 mg
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
Citations Miao Y, et al. (2012)PLoS One 7, e42318. Li P, et al. (2011)Cell 147, 815-26. Nohara A, et al. (2011)J Biol Chem 286, 33457-65.
NCBI CDK5
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias CDK5, CRK6, Cell division protein kinase 5, Tau protein kinase II catalytic subunit, kinase Cdk5
Lieferbar
Manufacturer - Applications
Western Blot: 1:500~1:1000
Shipping Temperature
blue ice or room temperature
Storage Conditions
Store antibody at -20°C for up to one year.
Molecular Weight
33 kDa
Manufacturer - Research Area
Phospho-Specific
Background
Proline-directed serine/threonine-protein kinase essential for neuronal cell cycle arrest and differentiation and may be involved in apoptotic cell death in neuronal diseases by triggering abortive cell cycle re-entry. Interacts with D1 and D3-type G1 cyclins. Phosphorylates SRC, NOS3, VIM/vimentin, p35/CDK5R1, MEF2A, SIPA1L1, SH3GLB1, PXN, PAK1, MCAM/MUC18, SEPT5, SYN1, DNM1, AMPH, SYNJ1, CDK16, RAC1, RHOA, CDC42, TONEBP/NFAT5, MAPT/TAU, MAP1B, histone H1, p53/TP53, HDAC1, APEX1, PTK2/FAK1, huntingtin/HTT, ATM, MAP2, NEFH and NEFM.
Modifications
Phospho-Specific
Protein Gi #
4826675
Purification
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Concentration
1 mg/ml
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen
CDK5 (phospho Tyr15) antibody was raised against a peptide sequence around phosphorylation site of Tyrosine15 (G-T-Y (p)-G-T) derived from Human CDK5.
Clonality
Polyclonal
NCBI Official Name
cyclin-dependent kinase 5
NCBI Organism
Homo sapiens
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0.1 mg
Lieferbar: In stock
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