« Zurück
Home /
CDK5 (phospho Tyr15) Antibody

CDK5 (phospho Tyr15) Antibody

Hersteller	ProSci
Kategorie	Oncology Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Targets for Rodent Neurosciences Aging & Neurological Disorders Neural Signaling Neural Epigenetics Neural Development Antibodies Western Blot Primary Antibodies By Organ Lung Cancer Bladder Cancer Breast Cancer Adhesion Molecule Markers Glial Cell Markers Cytoskeleton Markers Stem Cell Markers Astroglia Markers
Typ	Antibody Polyclonal
Specific against	Human, Mouse, Rat
Format	Liquid
Applikationen	WB
Menge	0.1 mg
Host	Rabbit
ArtNr	PRS-79-970-0.1mg
eClass 6.1	32160702
eClass 9.0	32160702
Lieferbar
Shipping	blue ice or RT
By Research Area	Phospho-Specific
Immunogen	CDK5 (phospho Tyr15) antibody was raised against a peptide sequence around phosphorylation site of Tyrosine15 (G-T-Y (p)-G-T) derived from Human CDK5.
Applications	Western Blot: 1:500~1:1000
Specificity	The antibody detects endogenous level of CDK5 only when phosphorylated at tyrosine 15.
Predicted Molecular Weight	33 kDa
Purification	Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality	Polyclonal
Isotype	IgG
Conjugate	Unconjugated
Buffer	Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration	1 mg/mL
Storage Conditions	Store antibody at -20˚ C for up to one year.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	Phospho-Specific
Ncbi Official Symbol	CDK5
Accession #	NP_001157882.1
Protein Gi #	4826675
Ncbi Gene Id #	1020
Ncbi Official Symbol	CDK5
Ncbi Official Full Name	cyclin-dependent kinase 5
Ncbi Organism	Homo sapiens
Swissprot #	Q00535
Background	Proline-directed serine/threonine-protein kinase essential for neuronal cell cycle arrest and differentiation and may be involved in apoptotic cell death in neuronal diseases by triggering abortive cell cycle re-entry. Interacts with D1 and D3-type G1 cyclins. Phosphorylates SRC, NOS3, VIM/vimentin, p35/CDK5R1, MEF2A, SIPA1L1, SH3GLB1, PXN, PAK1, MCAM/MUC18, SEPT5, SYN1, DNM1, AMPH, SYNJ1, CDK16, RAC1, RHOA, CDC42, TONEBP/NFAT5, MAPT/TAU, MAP1B, histone H1, p53/TP53, HDAC1, APEX1, PTK2/FAK1, huntingtin/HTT, ATM, MAP2, NEFH and NEFM.
Background References 1	Miao Y, et al. (2012)PLoS One 7, e42318. Li P, et al. (2011)Cell 147, 815-26. Nohara A, et al. (2011)J Biol Chem 286, 33457-65.
1st Image Caption	Western blot analysis of extracts from COS7 cells treated with EGF using Phospho-CDK5 (Tyr15) Antibody. The lane on the right is treated with the antigen-specific peptide.

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

Produkdatenblatt anfordern

Sicherheitsdatenblatt anfordern

Einfache Bestellung Periodische Bestellung

Menge: 0.1 mg

lieferbar

Lieferung vsl. bis 06.06.2024

Vergleichen

Auf den Wunschzettel

Weiterempfehlen per Mail

Angebot anfordern