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Anti-Glutaryllysine Rabbit pAb

ArtNr PTM-1151
Hersteller PTM Biolabs
Menge 100 ul
Kategorie
Typ Antibody Polyclonal
Format Lyophilized powder
Applikationen WB
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
Citations Yimin Cheng, et al. The involvement of lysine glutarylation and mitochondria in spermatic movement deficiency induced by hexavalent chromium. Heliyon, 2024. https://www.cell.com/heliyon/fulltext/S2405-8440(24)13917-5.
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Kglu
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Type
Primary Antibodies
Manufacturer - Category
Pan PTM Antibodies
Shipping Temperature
Ambient temperature
Storage Conditions
Store at -20°C. Avoid freeze/thaw cycles.
Molecular Weight
Multiple
Stability
Stable for 12 months from date of receipt/reconstitution.
Manufacturer - Research Area
Post-Translational Modificaiton
Manufacturer - Reactivity
All
Product description
Lysine glutarylation is a histone post-translational modification (PTM) that has been recently identified through integrated proteomic approaches and elaborate biochemistry analyses. This modification has been shown to be evolutionarily conserved across multiple species of prokaryotes and eukaryotes, and is present in a wide range of proteins, including both histones and non-histone substrates. Lysine glutarylation is a PTM that is regulated by SIRT5 and nutrient availability, and it has been demonstrated to impact various metabolic processes and mitochondrial functions.
Purification Method
Protein A and immunogen affinity purified
Manufacturer - Specificity
Anti-Glutaryllysine Rabbit pAb detects proteins post-translationally modified by glutarylation on lysine residues. This pan antibody recognizes glutarylated lysine independent of its surrounding sequences.
Formula
PBS, Glycerol, BSA
PTM
Glutaryl
Modification Site
Lys
Immunogen
Glutarylated lysine peptides
Clonality
Polyclonal
Background
Lysine glutarylation is a histone post-translational modification (PTM) that has been recently identified through integrated proteomic approaches and elaborate biochemistry analyses. This modification has been shown to be evolutionarily conserved across multiple species of prokaryotes and eukaryotes, and is present in a wide range of proteins, including both histones and non-histone substrates. Lysine glutarylation is a PTM that is regulated by SIRT5 and nutrient availability, and it has been demonstrated to impact various metabolic processes and mitochondrial functions.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ul
Lieferbar: In stock
lieferbar

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