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Anti-Citrulline-Histone H2A (Arg3) Rabbit pAb

Anti-Citrulline-Histone H2A (Arg3) Rabbit pAb

ArtNr	PTM-1305
Hersteller	PTM Biolabs
Menge	100 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Polyclonal
Format	Lyophilized powder
Applikationen	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	H2AR3cit
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Type	Primary Antibodies
Manufacturer - Category	Histone & Histone Modification Antibodies
Manufacturer - Targets	Histone H2A
Shipping Temperature	Ambient temperature
Storage Conditions	Store at -20°C. Avoid freeze/thaw cycles.
Molecular Weight	14
Stability	Stable for 12 months from date of receipt/reconstitution.
Manufacturer - Research Area	Epigenetics
Product description	Protein citrullination is an emerging PTM that results from the conversion of peptidyl arginine to peptidyl citrulline. Due to the exchange of an imine for a carbonyl group, this reaction is referred to as deimination. This PTM is catalyzed by the calcium-regulated peptidylarginine deiminases (PAD). Dysregulated PAD expression and aberrant protein citrullination have been implicated in numerous human diseases such as osteosarcoma, colorectal cancer, esophagus cancer and breast cancer.
Purification Method	Protein A and immunogen affinity purified
Manufacturer - Specificity	Anti-Citrulline-Histone H2A (Arg3) Rabbit pAb detects histone H2A only when it is citrullinated at Arg3.
Formula	PBS, Glycerol, BSA
PTM	Citrulline
Modification Site	Arg3
Immunogen	Citrullinated human histone H2A (Arg3) peptide
Clonality	Polyclonal
Background	Protein citrullination is an emerging PTM that results from the conversion of peptidyl arginine to peptidyl citrulline. Due to the exchange of an imine for a carbonyl group, this reaction is referred to as deimination. This PTM is catalyzed by the calcium-regulated peptidylarginine deiminases (PAD). Dysregulated PAD expression and aberrant protein citrullination have been implicated in numerous human diseases such as osteosarcoma, colorectal cancer, esophagus cancer and breast cancer.
Cellular Localization	Nucleus

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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PTM-1305-datasheet.pdf

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Menge: 100 ul

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Lieferung vsl. bis 19.02.2026

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