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Anti-PD-L1 Rabbit mAb

Anti-PD-L1 Rabbit mAb

ArtNr	PTM-5075
Hersteller	PTM Biolabs
Menge	100 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Monoclonal
Format	Lyophilized powder
Applikationen	WB, IHC-P
Clon	JRMR-129
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
Citations	Jiange Qiu, et al. Complementary roles of EP2 and EP4 receptors in malignant glioma. BRITISH JOURNAL OF PHARMACOLOGY, 2023. https://bpspubs.onlinelibrary.wiley.com/doi/abs/10.1111/bph.16148.
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	CD274, B7H1, PDCD1L1, PDCD1LG1
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Type	Primary Antibodies
Manufacturer - Category	Uncategorized
Manufacturer - Targets	PD-L1
Shipping Temperature	Ambient temperature
Storage Conditions	Store at -20°C. Avoid freeze/thaw cycles.
Stability	Stable for 12 months from date of receipt/reconstitution.
Manufacturer - Research Area	Cancer, Immunology
Product description	PD-1 is an immunoinhibitory receptor expressed by activated T cells, B cells, and myeloid cells. Engagement of PD-1 by PD-L1 leads to the inhibition of T cell receptor–mediated lymphocyte proliferation and cytokine secretion. In addition, PD-1 signaling can inhibit at least suboptimal levels of CD28-mediated costimulation. PD-L1 is expressed by antigen-presenting cells, including human peripheral blood monocytes stimulated with interferong, and activated human and murine dendritic cells.
Purification Method	Protein A purified
Formula	PBS, Glycerol, BSA
PTM	Unmodified
Clonality	Recombinant Monoclonal
Background	PD-1 is an immunoinhibitory receptor expressed by activated T cells, B cells, and myeloid cells. Engagement of PD-1 by PD-L1 leads to the inhibition of T cell receptor–mediated lymphocyte proliferation and cytokine secretion. In addition, PD-1 signaling can inhibit at least suboptimal levels of CD28-mediated costimulation. PD-L1 is expressed by antigen-presenting cells, including human peripheral blood monocytes stimulated with interferong, and activated human and murine dendritic cells.
Cellular Localization	Plasma membrane, Endosome

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100 ul

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Lieferung vsl. bis 24.07.2025

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