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Anti-Bcl-2 Rabbit mAb

Anti-Bcl-2 Rabbit mAb

ArtNr	PTM-5587
Hersteller	PTM Biolabs
Menge	100 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Monoclonal
Format	Lyophilized powder
Applikationen	WB, FC, IP, ICC, IHC-P
Clon	JRMR-10176-8
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
Citations	Xi Xu, et al. Venetoclax Overcomes Sorafenib Resistance in Acute Myeloid Leukemia by Targeting BCL2. Biology-Basel, 2023. https://www.mdpi.com/2079-7737/12/10/1337.
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	BCL2,Apoptosis regulator Bcl-2
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Type	Primary Antibodies
Manufacturer - Applications	WB, IHC-P, ICC/IF, FC, IP
Manufacturer - Category	Uncategorized
Manufacturer - Targets	Bcl-2
Shipping Temperature	Ambient temperature
Storage Conditions	Store at -20°C. Avoid freeze/thaw cycles.
Molecular Weight	26
Stability	Stable for 12 months from date of receipt/reconstitution.
Manufacturer - Research Area	Cell Biology, Immunology
Product description	Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release.
Purification Method	Protein A purified
Manufacturer - Specificity	Anti-Bcl-2 Rabbit mAb recognizes endogeneous level of Bcl-2 protein.
Formula	PBS, Glycerol, BSA
PTM	Unmodified
Immunogen	Recombinant human Bcl-2 fragment
Clonality	Recombinant Monoclonal
Background	Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release.
Cellular Localization	Membrane

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100 ul

lieferbar

Lieferung vsl. bis 19.02.2026

Express-Lieferung: 1 Tage sparen

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