Anti-HSP70 Mouse mAb

Organelle Marker Antibodies

Ambient temperature

Stable for 12 months from date of receipt/reconstitution.

Hsp70s are a family of conserved ubiquitously expressed heat shock proteins. Proteins with similar structure exist in virtually all living organisms. Intracellularly localized Hsp70s are an important part of the cell's machinery for protein folding, performing chaperoning functions, and helping to protect cells from the adverse effects of physiological stresses. Additionally, membrane-bound Hsp70s have been identified as a potential target for cancer therapies and their extracellularly localized counterparts have been identified as having both membrane-bound and membrane-free structures. The Hsp70 system interacts with extended peptide segments of proteins as well as partially folded proteins to cause aggregation of proteins in key pathways to downregulate activity.

PBS, Glycerol, BSA

Recombinant Monoclonal

Cytoplasm, Cytoskeleton, Nucleus, Secreted