Vergleich

Anti-CD272/BTLA Mouse mAb

ArtNr PTM-5772
Hersteller PTM Biolabs
Menge 100 ul
Kategorie
Typ Antibody Monoclonal
Format Lyophilized powder
Applikationen FC
Clon 10388
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG2a
Konjugat/Tag Unconjugated
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias B- and T-lymphocyte attenuator
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Type
Primary Antibodies
Manufacturer - Category
Uncategorized
Manufacturer - Targets
CD272/BTLA
Shipping Temperature
Ambient temperature
Storage Conditions
Store at -20°C. Avoid freeze/thaw cycles.
Stability
Stable for 12 months from date of receipt/reconstitution.
Manufacturer - Research Area
Immunology
Product description
CD272 is an inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2. It may interact in cis (on the same cell) or in trans (on other cells) with TNFRSF14. For cis interactions, it appears to play an immune regulatory role inhibiting naive T cells to maintain a resting state. For trans interactions, it predominates during adaptive immune response to provide survival signals to effector T cells.
Purification Method
Protein G purified
Formula
PBS, Glycerol, BSA
PTM
Unmodified
Clonality
Recombinant Monoclonal
Background
CD272 is an inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2. It may interact in cis (on the same cell) or in trans (on other cells) with TNFRSF14. For cis interactions, it appears to play an immune regulatory role inhibiting naive T cells to maintain a resting state. For trans interactions, it predominates during adaptive immune response to provide survival signals to effector T cells.
Cellular Localization
Cell membrane

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ul
Lieferbar: In stock
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