Anti-OGDH Mouse mAb

ArtNr	PTM-5974
Hersteller	PTM Biolabs
Menge	100 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Monoclonal
Format	Lyophilized powder
Applikationen	WB, ICC
Clon	10152
Specific against	Human (Homo sapiens), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG2b
Konjugat/Tag	Unconjugated
Citations	Haigang Cao, et al. Circular RNA circMYLK4 shifts energy metabolism from glycolysis to OXPHOS by binding to the calcium channel auxiliary subunit CACNA2D2. JOURNAL OF BIOLOGICAL CHEMISTRY, 2024. https://www.sciencedirect.com/science/article/pii/S0021925824019276.
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	2-oxoglutarate dehydrogenase complex component E1,E1o,HsOGDH,OGDC-E1,OGDH-E1,Alpha-ketoglutarate dehydrogenase (Alpha-KGDH-E1),Thiamine diphosphate (ThDP)-dependent 2-oxoglutarate dehydrogenase
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Type	Primary Antibodies
Manufacturer - Applications	WB, ICC/IF
Manufacturer - Category	Uncategorized
Manufacturer - Targets	OGDH
Shipping Temperature	Ambient temperature
Storage Conditions	Store at -20°C. Avoid freeze/thaw cycles.
Stability	Stable for 12 months from date of receipt/reconstitution.
Manufacturer - Research Area	Cardiovascular Biology, Metabolism
Product description	2-oxoglutarate dehydrogenase (E1) component of the 2-oxoglutarate dehydrogenase complex (OGDHC), which mediates the decarboxylation of alpha-ketoglutarate. The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO2.The 2-oxoglutarate dehydrogenase complex is mainly active in the mitochondrion.A fraction of the 2-oxoglutarate dehydrogenase complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl-CoA to histone succinyltransferase KAT2A.
Purification Method	Protein G purified
Formula	PBS, Glycerol, BSA
PTM	Unmodified
Clonality	Recombinant Monoclonal
Background	2-oxoglutarate dehydrogenase (E1) component of the 2-oxoglutarate dehydrogenase complex (OGDHC), which mediates the decarboxylation of alpha-ketoglutarate. The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO2.The 2-oxoglutarate dehydrogenase complex is mainly active in the mitochondrion.A fraction of the 2-oxoglutarate dehydrogenase complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl-CoA to histone succinyltransferase KAT2A.
Cellular Localization	Mitochondrion, Nucleus

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Menge: 100 ul

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Lieferung vsl. bis 19.02.2026

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