Anti-GST3/GSTP1 Rabbit mAb

Primary Antibodies

Uncategorized

Ambient temperature

Stable for 12 months from date of receipt/reconstitution.

Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the combination of many hydrophobic and electrophilic compounds with reduced glutathione. According to their biochemical, immunological and structural characteristics, mammalian cytoplasmic glutathione S-transferases are divided into eight cytoplasmic soluble subtypes (α, κ, μ, π, σ, θ, ζ, and ω). Glutathione transferase P1 (GSTπ) is a member of the π family of the glutathione transferase supergene family. It is highly expressed in the lungs and placenta. It is an important detoxification enzyme that metabolizes toxic compounds in the body and protects cells from Acutely toxic chemical substances play an important role in the attack. GSTP1 is overexpressed in the early stage of carcinogenesis and can be used as a tumor marker in tumor tissues. There are polymorphisms in the GSTP1 gene, and the difference in the activity of the corresponding enzymes in its expression leads to changes in the body's detoxification function, thereby affecting the body's susceptibility to tumors.

PBS, Glycerol, BSA

Recombinant Monoclonal

Cytoplasm, Mitochondrion, Nucleus