ArtNr |
PTM-6350 |
Hersteller |
PTM Biolabs
|
Menge |
100 ul |
Kategorie |
|
Typ |
Antibody Monoclonal |
Format |
Lyophilized powder |
Applikationen |
WB, ICC, IHC-P |
Clon |
11901 |
Specific against |
Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus) |
Host |
Rabbit |
Isotype |
IgG |
Konjugat/Tag |
Unconjugated |
Citations |
Xiao-Yi Xiong, et al. Astrocyte-derived lactate aggravates brain injury of ischemic stroke in mice by promoting the formation of protein lactylation. Theranostics, 2024. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11303085/. |
ECLASS 10.1 |
42030590 |
ECLASS 11.0 |
42030590 |
UNSPSC |
12352203 |
Alias |
HD1, RPD3L1 |
Versandbedingung |
Raumtemperatur |
Lieferbar |
|
Manufacturer - Type |
Primary Antibodies |
Manufacturer - Applications |
WB, IHC-P, ICC/IF |
Manufacturer - Category |
Loading Control Antibodies |
Manufacturer - Targets |
HDAC1 |
Shipping Temperature |
Ambient temperature |
Storage Conditions |
Store at -20°C. Avoid freeze/thaw cycles. |
Stability |
Stable for 12 months from date of receipt/reconstitution. |
Manufacturer - Research Area |
Epigenetics , Stem Cells, Cardiovascular Biology |
Product description |
Histone deacetylase 1 (HDAC1) is an enzyme that is encoded by the HDAC1 gene in human. Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. HDAC1 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2 MTA2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. |
Purification Method |
Protein A purified |
Formula |
PBS, Glycerol, BSA |
PTM |
Unmodified |
Clonality |
Recombinant Monoclonal |
Background |
Histone deacetylase 1 (HDAC1) is an enzyme that is encoded by the HDAC1 gene in human. Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. HDAC1 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2 MTA2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. |
Cellular Localization |
Nucleus |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.