Anti-PI3 Kinase p110 delta Rabbit mAb

Uncategorized

Ambient temperature

Stable for 12 months from date of receipt/reconstitution.

Phosphatidylinositol 4, 5-bisphosphate 3-kinase catalytic subunit delta isoform (PIK3CD) belongs to Class I Phosphoinositide-3-kinase (PI3K) which phosphorylates phosphatidylinositol (PI) and its phosphorylated derivatives at position 3 of the inositol ring to produce 3-phosphoinositides and uses ATP and PtdIns(4, 5)P2 (phosphatidylinositol 4, 5-bisphosphate) to generate phosphatidylinositol 3, 4, 5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology.

PBS, Glycerol, BSA

Recombinant Monoclonal

Cytoplasm