Vergleich

Anti-CD8 alpha Rabbit mAb

ArtNr PTM-6399
Hersteller PTM Biolabs
Menge 100 ul
Kategorie
Typ Antibody Monoclonal
Format Lyophilized powder
Applikationen WB, ICC
Clon JRMR-10564(2)-10
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias CD8a,MAL
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Type
Primary Antibodies
Manufacturer - Applications
WB, ICC/IF
Manufacturer - Category
Uncategorized
Manufacturer - Targets
CD8 alpha
Shipping Temperature
Ambient temperature
Storage Conditions
Store at -20°C. Avoid freeze/thaw cycles.
Stability
Stable for 12 months from date of receipt/reconstitution.
Manufacturer - Research Area
Immunology, Cancer
Product description
T-cell surface glycoprotein CD8 alpha chain (CD8 alpha) is an integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, CD8 alpha functions primarily as a coreceptor for MHC class I molecule:peptide complex. In NK-cells, the presence of CD8 alpha homodimers at the cell surface provides a survival mechanism allowing conjugation and lysis of multiple target cells. CD8 alpha homodimer molecules also promote the survival and differentiation of activated lymphocytes into memory CD8 T-cells.
Purification Method
Protein A purified
Formula
PBS, Glycerol, BSA
PTM
Unmodified
Clonality
Recombinant Monoclonal
Background
T-cell surface glycoprotein CD8 alpha chain (CD8 alpha) is an integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, CD8 alpha functions primarily as a coreceptor for MHC class I molecule:peptide complex. In NK-cells, the presence of CD8 alpha homodimers at the cell surface provides a survival mechanism allowing conjugation and lysis of multiple target cells. CD8 alpha homodimer molecules also promote the survival and differentiation of activated lymphocytes into memory CD8 T-cells.
Cellular Localization
Membrane and secreted

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ul
Lieferbar: In stock
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