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Anti-2-Hydroxyisobutyryllysine Rabbit pAb

Anti-2-Hydroxyisobutyryllysine Rabbit pAb

ArtNr	PTM-801
Hersteller	PTM Biolabs
Menge	100 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Polyclonal
Format	Lyophilized powder
Applikationen	WB
Specific against	other
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
Citations	Yimin Cheng, et al. The involvement of lysine glutarylation and mitochondria in spermatic movement deficiency induced by hexavalent chromium. Heliyon, 2024. https://www.cell.com/heliyon/fulltext/S2405-8440(24)13917-5.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Khib
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Type	Primary Antibodies
Manufacturer - Category	Pan PTM Antibodies
Shipping Temperature	Ambient temperature
Storage Conditions	Store at -20°C. Avoid freeze/thaw cycles.
Molecular Weight	Multiple
Stability	Stable for 12 months from date of receipt/reconstitution.
Manufacturer - Research Area	Post-Translational Modificaiton
Manufacturer - Reactivity	All
Product description	Histones are subjected to a variety of enzyme catalyzed modifications, including acetylation, methylation, ubiquitylation, and etc. Khib is a newly identified reversible modification controlling chromosome structure and gene transcription. The reversible lysine 2-hydroxyisobutyrylation has been well demonstrated in eukaryotic histones from worm to human. The unique structure and genomic localization of Khib suggest that it is mechanistically and functionally different from histone lysine acetylation.
Purification Method	Protein A and immunogen affinity purified
Manufacturer - Specificity	Anti-2-Hydroxyisobuyrylated Rabbit pAb detects proteins with 2-hydroxyisobutyrylated lysine residues. This pan antibody recognizes 2-hydroxyisobutyrylated lysine independent of its surrounding sequences.
Formula	PBS, Glycerol, BSA
PTM	2-Hydroxyisobutyryl
Modification Site	Lys
Immunogen	2-Hydroxyisobutyrylated lysine peptides
Clonality	Polyclonal
Background	Histones are subjected to a variety of enzyme catalyzed modifications, including acetylation, methylation, ubiquitylation, and etc. Khib is a newly identified reversible modification controlling chromosome structure and gene transcription. The reversible lysine 2-hydroxyisobutyrylation has been well demonstrated in eukaryotic histones from worm to human. The unique structure and genomic localization of Khib suggest that it is mechanistically and functionally different from histone lysine acetylation.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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PTM-801-datasheet.pdf

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Menge: 100 ul

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Lieferung vsl. bis 19.02.2026

Express-Lieferung: 1 Tage sparen

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