Anti-Prostatic Acid Phosphatase (PAP) Antibody

Primary Antibody

Prostatic Acid Phosphatase (PAP)

Store at -20°C in the dark. Under these conditions, the antibodies should have a shelf life of at least twelve months, provided they remain sterile.

10 mg/mL

About PAP: Mouse PAP is a 43, 698 dalton protein (381 amino acids, NCBI accession numberAAF23171) associated with prostatic cancer cells, as well as primary afferent sensory neurons involved in the pain pathway. This protein is an enzyme that dephosphorylates adenosine monophosphate (AMP) in the dorsal horn gray matter of the spinal cord, generating free adenosine. Injections of PAP into the dorsal horn of experimental mice has been shown to decrease pain perception by acting in an antinociceptive, antihyperalgesic, and antiallodynic fashion.

Recombinant mouse PAP protein was expressed in bacteria. Antibodies against this protein were prepared by injecting purified recombinant PAP into laying hens and purifying the IgY fraction from eggs collected from hyper-immunized hens. These antibodies have been validated with human, mouse and rat tissues.

Mouse Prostatic Acid Phosphatase (PAP) is a 43, 698 dalton protein (381 amino acids; NCBI accession number AAF23171) associated with prostatic cancer cells, as well as primary afferent sensory neurons involved in the pain pathway. This protein is an enzyme that dephosphorylates adenosine monophosphate (AMP) in the dorsal horn gray matter of the spinal cord, generating free adenosine. Injections of PAP into the dorsal horn of experimental mice has been shown to decrease pain perception by acting in an antinociceptive, antihyperalgesic, and antiallodynic fashion.

Polyclonal

1:500-1:1000

Recombinant mouse PAP expressed in Escherichia coli

Mixture of IgY fraction and affinity-purified antibodies

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.