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UBA1 Antibody - N-terminal region

ArtNr ARP58687_P050
Hersteller AVIVA Systems Biology
Menge 100 ul
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Rabbit (Oryctolagus cuniculus), Guinea Pig, Dog (Canine, Canis lupus familiaris), Horse (Equine), Cow (Bos taurus)
Host Rabbit
Sequence MEAGPPGSARPAEPGPCLSGQRGADHTASASLQSVAGTEPGRHPQAVAAV
Citations Rogers, L. M., Olivier, A. K., Meyerholz, D. K. & Dupuy, A. J. Adaptive immunity does not strongly suppress spontaneous tumors in a Sleeping Beauty model of cancer. J. Immunol. 190, 4393-9 (2013). 23475219
Ramser,J., (2008) Am. J. Hum. Genet. 82 (1), 188-193
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias A1S9,A1ST,GXP1,UBE1,A1S9T,AMCX1,POC20,SMAX2,UBA1A,UBE1X,VEXAS,CFAP124
Similar products UBA1
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Category
Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Polyclonal Antibodies/Cell Cycle Proteins, Root Catalog/Research Areas/E3 & Ubiquitin, Root Catalog/Research Areas/Disease Related, Root Catalog/Products/Polyclonal Antibodies/Trial Size Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies, Root Catalog/Products/Aviva Rabbit Polyclonal
Shipping Temperature
Wet Ice
Molecular Weight
116kDa
Species Tested
Human
Gene symbol
UBA1
Gene Fullname
Ubiquitin-like modifier activating enzyme 1
Protein size
1058
Product format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and storage
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Partner proteins
USP5; UBE2D2; UBC; FUS; ISG15; UBTD2; HUWE1; UBE2L3; UBE2D1; SUMO2; CDC34; UBE2K; UBE2W; UBE2R2; UBE2J1; UBE2T; UBE2S; UBE2C; UBE2E3; UBE2H; UBE2G2; UBE2G1; UBE2E2; UBE2E1; UBE2D3; UBE2B; UBE2A; UBI4; MDM2; TRIM25; XPNPEP1; EZR; MC1R; IPO5; FH; CTPS1; ATI
Description of target
UBA1 activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding an ubiquitin-E1 thioester and free AMP.The protein encoded by this gene catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. This gene complements an X-linked mouse temperature-sensitive defect in DNA synthesis, and thus may function in DNA repair. It is part of a gene cluster on chromosome Xp11.23. Alternatively spliced transcript variants that encode the same protein have been described.
Nucleotide accession_num
NM_003334
Protein accession_num
NP_003325
Protein name
Ubiquitin-like modifier-activating enzyme 1
Clonality
Polyclonal
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human UBA1
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Concentration
0.5 mg/ml

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ul
Lieferbar: In stock
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