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RASGRF1 antibody - middle region (ARP56515_P050)

ArtNr ARP56515_P050
Hersteller AVIVA Systems Biology
Menge 100ul
Kategorie
Typ Antibody Polyclonal
Format Lyophilized powder
Applikationen WB
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Porcine, Rabbit (Oryctolagus cuniculus), Fish, Guinea Pig, Bovine, Canine, Equine
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias CDC25, CDC25L, GNRP, GRF1, GRF55, H-GRF55, PP13187, ras-GRF1
Similar products RASGRF1
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Gene symbol
RASGRF1
Protein name
Ras-specific guanine nucleotide-releasing factor 1
Protein size
1273
Molecular weight
145kDa
Product format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Gene id
5923
Reconstitution and storage
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Partner proteins
EHD4. SNRNP70. CEBPA. ADRBK1. MYC. UBC. TNK2. YWHAE. USP8. RAC1. PRKACA. NTRK2. RRAS2. NTRK3. NTRK1. RHOA. YWHAB. PPP1R9B. MARK3. HRAS.
Description of target
The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Purification
Affinity Purified
Clonality
Polyclonal
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human RASGRF1
Drywet
Wet Ice

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100ul
Lieferbar: In stock
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