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HMGA1 Antibody

ArtNr OAEB00890
Hersteller AVIVA Systems Biology
Menge 100 ug
Kategorie
Typ Antibody Polyclonal
Applikationen IHC
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Dog (Canine, Canis lupus familiaris), Pig (Porcine, Sus scrofa domesticus), Cattle (Bovine)
Host Caprine
Sequence C-LASKQEKDGTEK
Citations * Chiappetta G, Botti G, Monaco M, Pasquinelli R, Pentimalli F, Di Bonito M,
D'Aiuto G, Fedele M, Iuliano R, Palmieri EA, Pierantoni GM, Giancotti V, Fusco
A.; HMGA1 protein overexpression in human breast carcinomas: correlation with ErbB2
expression.; Clin Cancer Res. 2004 Nov 15;10(22):7637-44; Pubmed 15569996
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias high mobility group protein A1;high mobility group protein HMG-I/HMG-Y;high mobility group protein R;HMGA1A;HMGIY;HMG-R;nonhistone chromosomal high-mobility group protein HMG-I/HMG-Y.
Similar products HMGA1
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Category
Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Monoclonal Antibodies/Transcription Regulation, Root Catalog/Research Areas/Cell Biology, Root Catalog/Research Areas/Chromatin & Nuclear Signaling, Root Catalog/Research Areas/Immunohistochemistry, Root Catalog/Research Areas/Transcription Factors, Root Catalog/Products/Primary Antibodies, Root Catalog/Research Areas/Cancer/Cancer Transcription Factor
Shipping Temperature
Wet Ice
Molecular Weight
11.7; 10.7
Manufacturer - Application Additional Information
Peptide ELISA: antibody detection limit dilution 1:32000.
Western Blot: Preliminary experiments gave an approx 50kDa band in Human Testis and Ovary lysates after 0.3ug/ml antibody staining.
Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 11.7kDa according to isoform a (also called HMG-I; NP_665906.1; NP_665908.1; NP_665911.1) and 10.7kDa according to isoform b ((also called HMG-Y; NP_002122.1; NP_665909.1; NP_665910.1; NP_665912.1). The 50kDa band was successfully blocked by incubation with the immunizing peptide.
IHC: In paraffin embedded human placenta shows strong nuclear staining. Recommended concentration: 4-6 ug/ml.
Gene symbol
HMGA1
Gene Fullname
high mobility group AT-hook 1
Product format
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Reconstitution and storage
Aliquot and store at -20C. Minimize freezing and thawing.
Protein accession_num
NP_665906.1
Protein name
High mobility group protein HMG-I/HMG-Y
Clonality
Polyclonal
Purification
Ammonium Sulfate Precipitated; Affinity Purified
Immunogen
HMGA1
Homology
Cow: 91%; Dog: 100%; Horse: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%
Manufacturer - Specificity
This antibody is expected to recognise isoform a (also called HMG-I; NP_665906.1; NP_665908.1) and isoform b (also called HMG-Y; NP_002122.1; NP_665909.1; NP_665910.1; NP_665912.1).
Concentration
0.5 mg/ml

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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