Goat Anti-SUR1 / ABCC8 Antibody

ArtNr	OAEB02180
Hersteller	AVIVA Systems Biology
Menge	100 ug
Kategorie	Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Regulation of Appetite Antibodies Western Blot Endocrine Regulation of Lipid Metabolism Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Dog (Canine, Canis lupus familiaris)
Host	Caprine
Purity	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Sequence	C-EFDKPEKLLSRKD
Citations	* de Wet H, Rees MG, Shimomura K, Aittoniemi J, Patch AM, Flanagan SE, Ellard S, Hattersley AT, Sansom MS, Ashcroft FM.; Increased ATPase activity produced by mutations at arginine-1380 in nucleotide-binding domain 2 of ABCC8 causes neonatal diabetes.; Proc Natl Acad Sci U S A. 2007 Nov 27;104(48):18988-92.; Pubmed 18025464
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	ABC36;ATP-binding cassette sub-family C member 8;ATP-binding cassette transporter sub-family C member 8;ATP-binding cassette,subfamily C (CFTR/MRP),member 8;ATP-binding cassette,sub-family C (CFTR/MRP),member 8;D930031B21Rik;HHF1;HI;HRINS;MRP8;PHHI;PNDM3;S;SU;sulfonylurea receptor;sulfonylurea receptor (hyperinsulinemia);sulfonylurea receptor 1;sulphonylurea receptor 1;Sur;Sur1;SUR1delta2;TNDM2.
Similar products	ABCC8
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Monoclonal Antibodies/Drugs and Drug Metabolism, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	177
Manufacturer - Application Additional Information	Peptide ELISA: antibody detection limit dilution 1:8000. Western Blot: Approx 170kDa band observed in Human Brain (Cerebellum) lysates (calculated MW of 177kDa according to NP_000343.2). Recommended concentration: 0.5-1.5ug/ml. An additional band of unknown identity was also consistently observed at 23kDa. This band was successfully blocked by incubation with the immunising peptide.
Gene symbol	Abcc8\|ABCC8
Gene Fullname	ATP binding cassette subfamily C member 8\|ATP-binding cassette, sub-family C (CFTR/MRP), member 8
Product format	Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20Â°C. Minimize freezing and thawing.
Reconstitution and storage	Aliquot and store at -20C. Minimize freezing and thawing.
Protein accession_num	NP_000343.2
Protein name	ATP-binding cassette sub-family C member 8
Clonality	Polyclonal
Purification	Ammonium Sulfate Precipitated; Affinity Purified
Immunogen	ABCC8
Homology	Cow: 100%; Horse: 100%; Human: 100%; Mouse: 92%; Pig: 92%; Rabbit: 92%; Rat: 92%
Concentration	0.5 mg/ml

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Menge: 100 ug

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