SMARCA4 Antibody (OAAH00026)

SMARCA4

1679

6597

This protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. Brg1 is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein Cd44

This Aviva monoclonal antibody is produced by immunizing mice with a peptide corresponding to amino-terminal residues of human Brg1.