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Goat Anti-TRPM7 / LTRPC7 Antibody

Goat Anti-TRPM7 / LTRPC7 Antibody

ArtNr	OAEB01441
Hersteller	AVIVA Systems Biology
Menge	100 ug
Kategorie	Antibodies Immunohistochemistry Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Dog (Canine, Canis lupus familiaris), Pig (Porcine, Sus scrofa domesticus)
Host	Caprine
Purity	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Sequence	C-TKESESTNSVRLML
Citations	* Sun HS, Jackson MF, Martin LJ, Jansen K, Teves L, Cui H, Kiyonaka S, Mori Y, Jones M, Forder JP, Golde TE, Orser BA, Macdonald JF, Tymianski M.; Suppression of hippocampal TRPM7 protein prevents delayed neuronal death in brain ischemia.; Nat Neurosci. 2009 Oct;12(10):1300-7. Epub 2009 Sep 6.; Pubmed 19734892 * Wei WL, Sun HS, Olah ME, Sun X, Czerwinska E, Czerwinski W, Mori Y, Orser BA, Xiong ZG, Jackson MF, Tymianski M, MacDonald JF.; TRPM7 channels in hippocampal neurons detect levels of extracellular divalent cations.; Proc Natl Acad Sci U S A. 2007 Oct 9;104(41):16323-8.; Pubmed 17913893 * Wei WL, Sun HS, Olah ME, Sun X, Czerwinska E, Czerwinski W, Mori Y, Orser BA, Xiong ZG, Jackson MF, Tymianski M, MacDonald JF.; TRPM7 channels in hippocampal neurons detect levels of extracellular divalent cations.; Proc Natl Acad Sci U S A. 2007 Oct 9;104(41):16323-8. Epub 2007 Oct 3.; Pubmed 17913893 * Kim BJ, Lim HH, Yang DK, Jun JY, Chang IY, Park CS, So I, Stanfield PR, Kim KW.; Melastatin-type transient receptor potential channel 7 is required for intestinal pacemaking activity.; Gastroenterology. 2005 Nov;129(5):1504-17.; Pubmed 16285951 * He Y, Yao G, Savoia C, Touyz RM.; Transient receptor potential melastatin 7 ion channels regulate magnesium homeostasis in vascular smooth muscle cells: role of angiotensin II.; Circ Res. 2005 Feb 4;96(2):207-15.; Pubmed 15591230 * He Y, Yao G, Savoia C, Touyz RM.; Transient receptor potential melastatin 7 ion channels regulate magnesium homeostasis in vascular smooth muscle cells: role of angiotensin II.; Circ Res. 2005 Feb 4;96(2):207-15. Epub 2004 Dec 9.; Pubmed 15591230 * Nadler MJ, Hermosura MC, Inabe K, Perraud AL, Zhu Q, Stokes AJ, Kurosaki T, Kinet JP, Penner R, Scharenberg AM, Fleig A.; LTRPC7 is a Mg.ATP-regulated divalent cation channel required for cell viability.; Nature 2001 May 31;411(6837):590-5; Pubmed 11385574
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	ALSPDC;CHAK;CHAK1;channel-kinase 1;long transient receptor potential channel 7;LTRPC ion channel family member 7;LTrpC-7;LTRPC7;transient receptor potential cation channel subfamily M member 7;transient receptor potential-phospholipase C-interacting kinase;TRP-PLIK.
Similar products	TRPM7
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Research Areas/Cell Biology, Root Catalog/Research Areas/Membrane & Traffic, Root Catalog/Research Areas/Cell Structure, Root Catalog/Research Areas/Phosphorylation, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	213; 213
Manufacturer - Application Additional Information	Peptide ELISA: antibody detection limit dilution 1:16000. Western Blot: Approx. 150kDa band observed in Human Brain (Cerebellum) lysates (calculated MW of 213kDa according to NP_060142.2). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Clark et al PLoS ONE. 2008 Mar 26; 3(3):e1876.; PMID: 18365021). Recommended concentration: 0.3- 1ug/ml.
Gene symbol	TRPM7
Gene Fullname	transient receptor potential cation channel subfamily M member 7
Product format	Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20Â°C. Minimize freezing and thawing.
Reconstitution and storage	Aliquot and store at -20C. Minimize freezing and thawing.
Protein accession_num	NP_060142.3
Protein name	Transient receptor potential cation channel subfamily M member 7
Clonality	Polyclonal
Purification	Ammonium Sulfate Precipitated; Affinity Purified
Immunogen	TRPM7
Homology	Cow: 92%; Dog: 92%; Guinea Pig: 100%; Horse: 85%; Human: 100%; Mouse: 92%; Rabbit: 100%; Rat: 92%; Sheep: 92%
Concentration	0.5 mg/ml

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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OAEB01441-datasheet.pdf

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Menge: 100 ug

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Lieferung vsl. bis 13.11.2025

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