IRF5 Antibody

ArtNr	OAEB02490
Hersteller	AVIVA Systems Biology
Menge	100 ug
Kategorie	Antibodies Immunohistochemistry Western Blot ELISA Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Cattle (Bovine)
Host	Caprine
Purity	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Sequence	C-QGPWPMHPAGMQ
Citations	* Hu G, Barnes BJ.; IRF-5 is a mediator of the death receptor-induced apoptotic signaling pathway.; J Biol Chem. 2009 Jan 30;284(5):2767-77.; Pubmed 19028697 * Ye L, Peng JS, Wang X, Wang YJ, Luo GX, Ho WZ.; Methamphetamine enhances Hepatitis C virus replication in human hepatocytes.; J Viral Hepat. 2008 Apr;15(4):261-70.; Pubmed 18307590 * Graham RR, Kyogoku C, Sigurdsson S, Vlasova IA, Davies LR, Baechler EC, Plenge RM, Koeuth T, Ortmann WA, Hom G, Bauer JW, Gillett C, Burtt N, Cunninghame Graham DS, Onofrio R, Petri M, Gunnarsson I, Svenungsson E, Ronnblom L, Nordmark G,; Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus.; Proc Natl Acad Sci U S A. 2007 Apr 17;104(16):6758-63.; Pubmed 17412832 * Ning S, Huye LE, Pagano JS.; Interferon regulatory factor 5 represses expression of the Epstein-Barr virus oncoprotein LMP1: braking of the IRF7/LMP1 regulatory circuit.; J Virol. 2005 Sep;79(18):11671-6.; Pubmed 16140744 * Barnes BJ, Moore PA, Pitha PM.; Virus-specific activation of a novel interferon regulatory factor, IRF-5, results in the induction of distinct interferon alpha genes.; J Biol Chem. 2001 Jun 29;276(26):23382-90.; Pubmed 11303025
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	interferon regulatory factor 5;SLEB10.
Similar products	IRF5
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Research Areas/Transcription Factors, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	56.0; 56.0; 57.8
Manufacturer - Application Additional Information	Peptide ELISA: antibody detection limit dilution 1:32000. Western Blot: Approx 57kDa band observed in lysates of cell line A549. In transfected HEK293 transiently expressing IRF5 a strong band of approx. 60kDa is observed. This band is not observed in the non-transfected HEK293. The calculated molecular size is 57.8kDa according to NP_001092099.1. Recommended concentration, 0.1-0.3ug/ml.
Gene symbol	IRF5
Gene Fullname	interferon regulatory factor 5
Product format	Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20Â°C. Minimize freezing and thawing.
Reconstitution and storage	Aliquot and store at -20C. Minimize freezing and thawing.
Protein accession_num	NP_002191.1
Protein name	Interferon regulatory factor 5
Clonality	Polyclonal
Purification	Ammonium Sulfate Precipitated; Affinity Purified
Immunogen	IRF5
Homology	Cow: 91%; Dog: 75%; Guinea Pig: 91%; Horse: 91%; Human: 100%; Mouse: 91%; Rabbit: 83%; Rat: 91%
Concentration	0.5 mg/ml

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Menge: 100 ug

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