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APTX Antibody - middle region

ArtNr ARP32885_P050
Hersteller AVIVA Systems Biology
Menge 100 ul
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB
Specific against Human (Homo sapiens), Rabbit (Oryctolagus cuniculus), Guinea Pig, Dog (Canine, Canis lupus familiaris), Horse (Equine), Cow (Bos taurus)
Host Rabbit
Sequence YPYIVEFEEEAKNPGLETHRKRKRSGNSDSIERDAAQEAEAGTGLEPGSN
Citations Yoon,G., (2008) J. Neurol. Neurosurg. Psychiatr. 79 (2), 234-236
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias AOA,AOA1,AXA1,EAOH,EOAHA,FHA-HIT
Similar products APTX
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Category
Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Polyclonal Antibodies/Transcription Factor, Root Catalog/Research Areas/Chromatin & Nuclear Signaling, Root Catalog/Research Areas/DNA Damage & Repair, Root Catalog/Research Areas/Disease Related, Root Catalog/Research Areas/DNA\/RNA\/Protein Interactions, Root Catalog/Products/Polyclonal Antibodies/Trial Size Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies, Root Catalog/Products/Aviva Rabbit Polyclonal
Shipping Temperature
Wet Ice
Molecular Weight
35kDa
Species Tested
Human
Gene symbol
APTX
Gene Fullname
Aprataxin
Protein size
306
Product format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and storage
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Partner proteins
PNMA1; UBC; SUMO1; NEDD8; LIG3; HSPA4; XRCC1; DDX21; CNTROB; TSPYL2; CALCOCO1; SYT17; ZNF639; MAPKBP1; CEP350; PICK1; XRCC4; TRIM37; MBP; HIVEP1; BANF1; PARP1; TP53;
Description of target
APTX is a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. The protein may play a role in single-stranded DNA repair. Mutations in this gene have been associated with ataxia-ocular apraxia. Multiple transcript variants encoding distinct isoforms have been identified for this gene, however, the full length nature of some variants has not been determined. This gene encodes a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. The encoded protein may play a role in single-stranded DNA repair. Mutations in this gene have been associated with ataxia-ocular apraxia. Multiple transcript variants encoding distinct isoforms have been identified for this gene, however, the full length nature of some variants has not been determined.
Nucleotide accession_num
NM_175069
Protein accession_num
NP_778239
Protein name
Aprataxin
Clonality
Polyclonal
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human APTX
Homology
Cow: 77%; Dog: 86%; Guinea Pig: 79%; Horse: 92%; Human: 100%; Rabbit: 86%
Concentration
0.5 mg/ml
Sample Type Confirmation

APTX is supported by BioGPS gene expression data to be expressed in HEK293T, HepG2

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ul
Lieferbar: In stock
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