ArtNr |
ARP63409_P050 |
Hersteller |
AVIVA Systems Biology
|
Menge |
100ul |
Kategorie |
|
Typ |
Antibody Polyclonal |
Format |
Lyophilized powder |
Applikationen |
WB |
Specific against |
Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Porcine, Rabbit (Oryctolagus cuniculus), Fish, Guinea Pig, Bovine, Canine, Equine, Goat (Caprine, Capra aegagrus hircus), Sheep (Ovine, Ovis aries) |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
C75990, D15Ertd23e, Dgat |
Similar products |
C75990, D15Ertd23e, Dgat |
Lieferbar |
|
Gene symbol |
Dgat1 |
Protein name |
Diacylglycerol O-acyltransferase 1 |
Protein size |
498 |
Molecular weight |
57kDa |
Product format |
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Gene id |
13350 |
Reconstitution and storage |
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Description of target |
Dgat1 catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. In contrast to DGAT2 it is not essential for survival. It may be involved in VLDL (very low density lipoprotein) assembly. In liver, Dgat1 plays a role in esterifying exogenous fatty acids to glycerol. It functions as the major acyl-CoA retinol acyltransferase (ARAT) in the skin, where it acts to maintain retinoid homeostasis and prevent retinoid toxicity leading to skin and hair disorders. |
Homology |
Cow: 100%; Dog: 93%; Goat: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 86% |
Purification |
Affinity Purified |
Clonality |
Polyclonal |
Immunogen |
The immunogen is a synthetic peptide directed towards the N-terminal region of Mouse Dgat1 |
Drywet |
Wet Ice |
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