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Goat Anti-Hamartin / TSC1 (isoform 1) Antibody

ArtNr OAEB01142
Hersteller AVIVA Systems Biology
Menge 100 ug
Kategorie
Typ Antibody Polyclonal
Applikationen WB, IHC
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Dog (Canine, Canis lupus familiaris)
Host Caprine
Purity Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Sequence C-QLHIMDYNETHHEH
Citations * Chan JA, Zhang H, Roberts PS, Jozwiak S, Wieslawa G, Lewin-Kowalik J, Kotulska K, Kwiatkowski DJ.; Pathogenesis of tuberous sclerosis subependymal giant cell astrocytomas: biallelic inactivation of TSC1 or TSC2 leads to mTOR activation.; J Neuropathol Exp Neurol. 2004 Dec;63(12):1236-42.; Pubmed 15624760
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias ham;hamartin;LAM;truncated hemartin;TSC;tuberous sclerosis 1 protein;tuberous sclerosis 1 protein homolog.
Similar products TSC1
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Category
Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Polyclonal Antibodies/RNA Binding Proteins, Root Catalog/Research Areas/Cell Biology, Root Catalog/Research Areas/Developmental Biology, Root Catalog/Research Areas/Stem Cells, Root Catalog/Research Areas/Meiosis\/Mitosis\/Cell Cycle, Root Catalog/Research Areas/Immunohistochemistry, Root Catalog/Research Areas/Cell Differentiation, Root Catalog/Products/Primary Antibodies
Shipping Temperature
Wet Ice
Molecular Weight
130
Manufacturer - Application Additional Information
Peptide ELISA: antibody detection limit dilution 1:128000.
Western Blot: Approx 150kDa band observed in Human Brain lysates (calculated MW of 130kDa according to NP_000359.1). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Miloloza et al Hum Mol Genet. 2000 Jul 22; 9(12):1721-7; PMID: 10915759). In transfected HEK293 transiently expressing Human TSC1 a band of approx. 120kDa is observed. This band is not observed in the non-transfected HEK293. Recommended concentration: 0.1-0.3ug/ml..
Gene symbol
Tsc1|TSC1
Gene Fullname
TSC complex subunit 1
Product format
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Reconstitution and storage
Aliquot and store at -20C. Minimize freezing and thawing.
Protein accession_num
NP_000359.1
Protein name
Hamartin
Clonality
Polyclonal
Purification
Ammonium Sulfate Precipitated; Affinity Purified
Immunogen
TSC1
Homology
Dog: 100%; Guinea Pig: 85%; Horse: 100%; Human: 100%; Mouse: 92%; Rabbit: 85%; Rat: 100%; Zebrafish: 84%
Concentration
0.5 mg/ml

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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