SLC6A5 Antibody - N-terminal region (ARP43872_P050)

sodium- and chloride-dependent glycine transporter 2

43kDa

9152

This gene encodes a sodium- and chloride-dependent glycine neurotransmitter transporter. This integral membrane glycoprotein is responsible for the clearance of extracellular glycine during glycine-mediated neurotransmission. This protein is found in glycinergic axons and maintains a high presynaptic pool of neurotransmitter at glycinergic synapses. Mutations in this gene cause hyperekplexia; a heterogenous neurological disorder characterized by exaggerated startle responses and neonatal apnea. Two transcript variants encoding different isoforms have been found for this gene.

Affinity Purified

The immunogen is a synthetic peptide directed towards the N-terminal region of human SLC6A5