RNF213 Antibody - N-terminal region

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118kDa

RNF213

1063

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

This gene encodes a protein containing a C3HC4-type RING finger domain, which is a specialized type of Zn-finger that binds two atoms of zinc and is thought to be involved in mediating protein-protein interactions. The protein also contains an AAA domain, which is associated with ATPase activity. This gene is a susceptibility gene for Moyamoya disease, a vascular disorder of intracranial arteries. This gene is also a translocation partner in anaplastic large cell lymphoma and inflammatory myofibroblastic tumor cases, where a t(2; 17)(p23; q25) translocation has been identified with the anaplastic lymphoma kinase (ALK) gene on chromosome 2, and a t(8; 17)(q24; q25) translocation has been identified with the MYC gene on chromosome 8.

NP_066005

Polyclonal

The immunogen is a synthetic peptide directed towards the N-terminal region of Human RNF213

0.5 mg/ml