NKX2-1 Antibody - N-terminal region

Polyclonal Antibody

Wet Ice

Human

NK2 homeobox 1

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias ' TTF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription.

Polyclonal

The immunogen for Anti-NKX2-1 antibody is: synthetic peptide directed towards the N-terminal region of Human NKX21