NCOR1 Antibody - N-terminal region

Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies

Wet Ice

WB: 1:1000
IHC-P: 1:50~100
IF: 1:10~50

Liquid. PBS with 0.09% (W/V) sodium azide.

NCOR1 mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. The gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. An alternatively spliced transcript variant has been described, but its full length sequence has not been determined.

Nuclear receptor corepressor 1

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Human; Mouse