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IL4R Antibody

ArtNr OAAF01124
Hersteller AVIVA Systems Biology
Menge 100 ug
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB, IF, ICC, ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host Rabbit
Citations Idzerda R.L., J. Exp. Med. 171:861-873(1990).
Galizzi J.-P., Int. Immunol. 2:669-675(1990).
Kruse S., Int. Immunol. 11:1965-1970(1999)
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias CD124;IL-4 receptor subunit alpha;IL4R nirs variant 1;IL4RA;IL-4RA;interleukin 13 receptor;interleukin-4 receptor alpha chain;interleukin-4 receptor subunit alpha.
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Category
Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature
Wet Ice
Molecular Weight
89 kDa
Manufacturer - Application Additional Information
WB: 1:500~1:3000; IF: 1:100~1:500; ELISA: 1:1000
Gene symbol
IL4R
Gene Fullname
interleukin 4 receptor
Product format
Liquid
Reconstitution and storage
-20°C
Description of target
Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2.
Protein accession_num
NP_000409.1
Protein name
Interleukin-4 receptor subunit alpha
Clonality
Polyclonal
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen
The antiserum was produced against synthesized peptide derived from human IL-4R/CD124.
Dilution
The optimal working dilution should be determined by the end user.
Manufacturer - Specificity
IL-4R/CD124 (Ab-497) antibody detects endogenous levels of total IL-4R/CD124 protein.
Formulation
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
lieferbar

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