IGF2R Antibody

ArtNr	OAAF01205
Hersteller	AVIVA Systems Biology
Menge	100 ug
Kategorie	Oncology Metabolism Diabetes Antibodies By Cell Type Carcinoma Flow Cytometry Immunohistochemistry ELISA Immunofluorescence Immunocytochemistry Primary Antibodies Immunostaining Immunochemistry
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	IF, IHC, ICC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Citations	Thomas L. Wise, Cancer Res., Feb 2006; 66: 1327 - 1336. Florian M. Pauler, Genome Res., Oct 2005; 15: 1379 - 1387. Oskar W. Smrzka, Hum. Mol. Genet., Oct 1995; 4: 1945 - 1952.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	300 kDa mannose 6-phosphate receptor;cation-independent mannose-6-phosphate receptor;CD222;CI Man-6-P receptor;CI-M6PR;CIMPR;IGF-II receptor;Insulin-like growth factor 2 receptor;insulin-like growth factor II receptor;M6P/IGF2 receptor;M6P/IGF2R;M6P-R;MPR 300;MPR1;MPR300;MPRI.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	Enzyme-linked immunosorbent assay\|Immunocytochemistry\|Immunofluorescence\|Immunohistochemistry\|Immunohistochemistry-Paraffin
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	274 kDa
Manufacturer - Application Additional Information	IHC: 1:50~1:100; IF: 1:100~1:500; ELISA: 1:5000
Gene symbol	IGF2R
Gene Fullname	insulin like growth factor 2 receptor
Product format	Liquid
Reconstitution and storage	-20°C
Description of target	Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4.
Protein accession_num	NP_000867.2
Protein name	Cation-independent mannose-6-phosphate receptor
Clonality	Polyclonal
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen	The antiserum was produced against synthesized peptide derived from human IGF2R.
Dilution	The optimal working dilution should be determined by the end user.
Manufacturer - Specificity	IGF2R antibody detects endogenous levels of total IGF2R protein.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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OAAF01205-datasheet.pdf

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Menge: 100 ug

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Lieferung vsl. bis 13.11.2025

Express-Lieferung: 9 Tage sparen

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