NFAT5 Antibody

ArtNr	OAAF01209
Hersteller	AVIVA Systems Biology
Menge	100 ug
Kategorie	Neuroscience Neuroinflammation Antibodies Cell Biology Cell Status Cell Metabolism Immunohistochemistry ELISA Immunofluorescence Oxidative Stress Primary Antibodies Immunostaining
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	IF, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Citations	Nagase T., DNA Res. 5:355-364(1998). Lopez-Rodriguez C., Proc. Natl. Acad. Sci. U.S.A. 96:7214-7219(1999). Miyakawa H., Proc. Natl. Acad. Sci. U.S.A. 96:2538-2542(1999)
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	glutamine rich protein H65;NF-AT5;NFATL1;NFAT-like protein 1;NFATZ;nuclear factor of activated T-cells 5;nuclear factor of activated T-cells 5,tonicity-responsive;OREBP;osmotic response element-binding protein;T-cell transcription factor NFAT5;TonE-binding protein;TONEBP;tonicity-responsive enhancer-binding protein.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	Enzyme-linked immunosorbent assay\|Immunofluorescence\|Immunohistochemistry\|Immunohistochemistry-Paraffin
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	165 kDa
Manufacturer - Application Additional Information	IHC: 1:50~1:100; ELISA: 1:1000
Gene symbol	NFAT5
Gene Fullname	nuclear factor of activated T cells 5
Product format	Liquid
Reconstitution and storage	-20°C
Description of target	Transcription factor involved, among others, in the transcriptional regulation of osmoprotective and inflammatory genes. Mediates the transcriptional response to hypertonicity (PubMed:10051678). Positively regulates the transcription of LCN2 and S100A4 genes; optimal transactivation of these genes requires the presence of DDX5/DDX17 (PubMed:22266867). Binds the DNA consensus sequence 5'-[ACT][AG]TGGAAA[CAT]A[TA][ATC][CA][ATG][GT][GAC][CG][CT]-3' (PubMed:10377394).
Protein accession_num	NP_001106649.1
Protein name	Nuclear factor of activated T-cells 5
Clonality	Polyclonal
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen	The antiserum was produced against synthesized peptide derived from human NFAT5.
Dilution	The optimal working dilution should be determined by the end user.
Manufacturer - Specificity	NFAT5 antibody detects endogenous levels of total NFAT5 protein.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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OAAF01209-datasheet.pdf

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Menge: 100 ug

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Lieferung vsl. bis 13.11.2025

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