TTK Antibody

ArtNr	OAAF01564
Hersteller	AVIVA Systems Biology
Menge	100 ug
Kategorie	Oncology Antibodies By Cell Type Blastoma Carcinoma Hematology Myeloma Mesothelioma Immunohistochemistry Western Blot ELISA Immunofluorescence Primary Antibodies Immunostaining
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IF, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Citations	Targeting dual specificity protein kinase TTK attenuates tumorigenesis of glioblastoma. Oncotarget. 9, 3081-3088 (2018). 29423030 Mills G.B., J. Biol. Chem. 267:16000-16006(1992). Ota T., Nat. Genet. 36:40-45(2004). Mungall A.J., Nature 425:805-811(2003)
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	cancer/testis antigen 96;CT96;dual specificity protein kinase TTK;ESK;monopolar spindle 1 kinase;monopolar spindle 1-like 1;MPH1;MPS1;MPS1L1;phosphotyrosine picked threonine kinase;phosphotyrosine picked threonine-protein kinase;PYT.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	Enzyme-linked immunosorbent assay\|Immunofluorescence\|Immunohistochemistry\|Immunohistochemistry-Paraffin\|Western blot
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	97 kDa
Manufacturer - Application Additional Information	WB: 1:500~1:3000; IHC: 1:50~1:100; ELISA: 1:10000
Gene symbol	TTK
Gene Fullname	TTK protein kinase
Product format	Liquid
Reconstitution and storage	-20°C
Description of target	Phosphorylates proteins on serine, threonine, and tyrosine. Probably associated with cell proliferation. Essential for chromosome alignment by enhancing AURKB activity (via direct CDCA8 phosphorylation) at the centromere, and for the mitotic checkpoint.
Protein accession_num	NP_001160163.1
Protein name	Dual specificity protein kinase TTK
Clonality	Polyclonal
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen	The antiserum was produced against synthesized peptide derived from human TTK.
Dilution	The optimal working dilution should be determined by the end user.
Manufacturer - Specificity	TTK (Ab-676) antibody detects endogenous levels of total TTK protein.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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OAAF01564-datasheet.pdf

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Menge: 100 ug

lieferbar

Lieferung vsl. bis 13.11.2025

Express-Lieferung: 9 Tage sparen

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