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HSPH1 Antibody

ArtNr OAAF01833
Hersteller AVIVA Systems Biology
Menge 100 ug
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB, IF, IHC, ICC, ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host Rabbit
Isotype IgG
Citations Kunihiko Yasuda, J. Biol. Chem., Dec 1995; 270: 29718.
Nobuyuki Yamagishi, Eur. J. Biochem., Aug 2002; 269: 4143.
Nobuyuki Yamagishi, J. Biol. Chem., Oct 2004; 279: 41727 - 41733.
Nobuyuki Yamagishi, J. Biochem. (Tokyo), Aug 2002; 132: 271 - 2
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias antigen NY-CO-25;heat shock 105kDa/110kDa protein 1;Heat shock 110 kDa protein;heat shock protein 105 kDa;HSP105;HSP105A;HSP105B;NY-CO-25.
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Applications
Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot
Manufacturer - Category
Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature
Wet Ice
Molecular Weight
96 kDa
Manufacturer - Application Additional Information
WB: 1:500~1000
IHC: 1:50~100
IF: 1:100~500
ELISA: 1:10000
Gene symbol
HSPH1
Gene Fullname
heat shock protein family H (Hsp110) member 1
Product format
Liquid. PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Reconstitution and storage
-20°C
Description of target
Acts as a nucleotide-exchange factor (NEF) for chaperone proteins HSPA1A and HSPA1B, promoting the release of ADP from HSPA1A/B thereby triggering client/substrate protein release (PubMed:24318877). Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities (By similarity).
Protein accession_num
NP_006635.2
Protein name
Heat shock protein 105 kDa
Clonality
Polyclonal
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen
The antiserum was produced against synthesized peptide derived from human HSP105.
Dilution
The optimal working dilution should be determined by the end user.
Manufacturer - Specificity
HSP105 antibody detects endogenous levels of total HSP105 protein.
Concentration
1 mg/ml

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
lieferbar

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