SOX18 Antibody

ArtNr	OAAF02331
Hersteller	AVIVA Systems Biology
Menge	100 ug
Kategorie	Oncology Neuroscience Molecular Targets for Neuroscience Neural Adhesion Molecules Antibodies By Cell Type Blastoma Carcinoma Hematology Leukemia Adenocarcinoma Immunohistochemistry Western Blot ELISA Immunofluorescence Primary Antibodies Immunostaining
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IF, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Monkey (Cynomolgus, Simian)
Host	Rabbit
Citations	Daniels R.J., Hum. Mol. Genet. 10:339-352(2001). Martin J., Nature 432:988-994(2004). The MGC Project Team, Genome Res. 14:2121-2127(2004).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CMD1;CMPD1;HLTRS;HLTS;SRA1;SRXX2;SRXY10;SRY (sex determining region Y)-box 17;SRY (sex determining region Y)-box 18;SRY (sex determining region Y)-box 8;SRY (sex determining region Y)-box9;SRY (sex-determining region Y)-box 9 protein;SRY-box 17;SRY-box 18;SRY-box 8;SRY-box 9;SRY-related HMG-box transcription factor SOX17;SRY-related HMG-box,gene 9;transcription factor SOX-17;transcription factor SOX-18;transcription factor SOX-8;transcription factor SOX-9;VUR3.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	Enzyme-linked immunosorbent assay\|Immunofluorescence\|Immunohistochemistry\|Immunohistochemistry-Paraffin\|Western blot
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	47 kDa
Manufacturer - Application Additional Information	WB: 1:500~1:3000; IHC: 1:50~1:100; ELISA: 1:10000
Gene symbol	SOX17\|SOX18\|SOX8\|SOX9
Gene Fullname	SRY-box transcription factor 17\|SRY-box transcription factor 18\|SRY-box transcription factor 8\|SRY-box transcription factor 9
Product format	Liquid
Reconstitution and storage	-20°C
Description of target	Acts as transcription regulator that binds target promoter DNA and bends the DNA. Binds to the sequences 5'-AACAAT-'3 or 5'-AACAAAG-3'. Modulates transcriptional regulation via WNT3A. Inhibits Wnt signaling. Promotes degradation of activated CTNNB1. Plays a key role in the regulation of embryonic development. Required for normal looping of the embryonic heart tube. Required for normal development of the definitive gut endoderm. Probable transcriptional activator in the premeiotic germ cells (By similarity).\|Binds to the consensus sequence 5'-AACAAAG-3' and is able to trans-activate transcription via this site.\|May play a role in central nervous system, limb and facial development. May be involved in male sex determination. Binds the consensus motif 5'-[AT][AT]CAA[AT]G-3' (By similarity).\|Transcriptional regulator (PubMed:24038782). Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219 (By similarity). Plays a role in chondrocyte differentiation (By similarity). Important for normal skeletal development (PubMed:24038782).
Protein accession_num	NP_060889.1
Protein name	Transcription factor SOX-17\|Transcription factor SOX-18\|Transcription factor SOX-8\|Transcription factor SOX-9
Clonality	Polyclonal
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen	The antiserum was produced against synthesized peptide derived from human SOX8/9/17/18.
Dilution	The optimal working dilution should be determined by the end user.
Manufacturer - Specificity	SOX8/9/17/18 antibody detects endogenous levels of total SOX8/9/17/18 protein.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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OAAF02331-datasheet.pdf

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Menge: 100 ug

lieferbar

Lieferung vsl. bis 29.01.2026

Express-Lieferung: 17 Tage sparen

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