MALT1 Antibody

ArtNr	OAAF03043
Hersteller	AVIVA Systems Biology
Menge	100 ug
Kategorie	Oncology Neuroscience Neural Lineage Markers Neuroinflammation Metabolism Diabetes Molecular Targets for Neuroscience Neural Signaling Antibodies By Cell Type Hematology Leukemia Lymphoma Immunohistochemistry Western Blot ELISA Immunofluorescence Immunocytochemistry Primary Antibodies By Organ Immunostaining Lymphatic System Cancer Neuronal Cell Markers Immunochemistry
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IF, IHC, ICC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Citations	Dierlamm J., Blood 93:3601-3609(1999). Akagi T., Oncogene 18:5785-5794(1999). Uren A.G., Mol. Cell 6:961-967(2000).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	caspase-like protein;IMD12;MALT lymphoma-associated translocation;MALT1 protease;MLT;MLT1;mucosa associated lymphoid tissue lymphoma translocation gene 1;mucosa-associated lymphoid tissue lymphoma translocation protein 1;Paracaspase;paracaspase-1;PCASP1.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	Enzyme-linked immunosorbent assay\|Immunocytochemistry\|Immunofluorescence\|Immunohistochemistry\|Immunohistochemistry-Paraffin\|Western blot
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	92 kDa
Manufacturer - Application Additional Information	WB: 1:500~1:3000; ELISA: 1:10000
Gene symbol	MALT1
Gene Fullname	MALT1 paracaspase
Product format	Liquid
Reconstitution and storage	-20°C
Description of target	Enhances BCL10-induced activation of NF-kappa-B. Involved in nuclear export of BCL10. Binds to TRAF6, inducing TRAF6 oligomerization and activation of its ligase activity. Has ubiquitin ligase activity. MALT1-dependent BCL10 cleavage plays an important role in T-cell antigen receptor-induced integrin adhesion. Involved in the induction of T helper 17 cells (Th17) differentiation. Cleaves RC3H1 and ZC3H12A in response to T-cell receptor (TCR) stimulation which releases their cooperatively repressed targets to promote Th17 cell differentiation (By similarity).
Protein accession_num	NP_006776.1
Protein name	Mucosa-associated lymphoid tissue lymphoma translocation protein 1
Clonality	Polyclonal
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen	The antiserum was produced against synthesized peptide derived from human MALT1.
Dilution	The optimal working dilution should be determined by the end user.
Manufacturer - Specificity	MALT1 antibody detects endogenous levels of total MALT1 protein.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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OAAF03043-datasheet.pdf

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Menge: 100 ug

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Lieferung vsl. bis 29.01.2026

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