TLR1 Antibody

ArtNr	OAPB00357
Hersteller	AVIVA Systems Biology
Menge	0.1 mg
Kategorie	Oncology Neuroscience Neural Lineage Markers Neuroinflammation Metabolism Regulation of Appetite Antibodies By Cell Type Hematology Leukemia Lymphoma Immunohistochemistry Western Blot ELISA Immunofluorescence Primary Antibodies Immunostaining Neurodegeneration Markers
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IF, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Konjugat/Tag	Unconjugated
Citations	Vogel SN, Fitzgerald KA, and Fenton MJ. TLRs: differential adapter utilization by toll-like receptors mediates TLR-specific patterns of gene expression. Mol. Interv. 2003; 3:466-77.;Takeda K, Kaisho T, and Akira S. Toll-like receptors. Annu. Rev. Immunol. 2003; 21:335-76.;Janeway CA Jr. and Medzhitov R. Innate immune recognition. Annu. Rev. Immunol. 2002; 20:197-216.;Oâ€™Neill LAJ, Fitzgerald FA, and Bowie AG. The Toll-IL-1 receptor adaptor family grows to five members. Trends in Imm. 2003; 24:286-9.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CD281;rsc786;TIL;TIL. LPRS5;toll/interleukin-1 receptor-like protein;toll-like receptor 1.
Similar products	TLR1
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	Enzyme-linked immunosorbent assay\|Immunofluorescence\|Immunohistochemistry-Paraffin\|Western blot
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	Predicted: 86 kDa Observed: 90 kDa
Manufacturer - Application Additional Information	TLR1 antibody can be used for detection of TLR1 by Western blot at 1 to 2 ug/ml. (Optimal dilution should be determined by user)
Gene symbol	TLR1
Gene Fullname	toll like receptor 1
Product format	Liquid. TLR1 Antibody is supplied in PBS containing 0.02% sodium azide.
Reconstitution and storage	TLR1 antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Description of target	Participates in the innate immune response to microbial agents. Specifically recognizes diacylated and triacylated lipopeptides. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides (PubMed:21078852). Forms the activation cluster TLR2:TLR1:CD14 in response to triacylated lipopeptides, this cluster triggers signaling from the cell surface and subsequently is targeted to the Golgi in a lipid-raft dependent pathway (PubMed:16880211). Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
Nucleotide accession_num	NM_003263.3; XM_005262662.3; XM_006714028.2
Protein accession_num	https://www.ncbi.nlm.nih.gov/protein/CAG38593
Protein name	TLR1 [Homo sapiens]\|Toll-like receptor 1
Clonality	Polyclonal
Purification	Affinity Purified
Immunogen	TLR1 antibody was raised against a peptide corresponding to 16 amino acids near the amino terminus of human TLR1. The immunogen is located within amino acids 160 - 210 of TLR1.
Homology	Human; Mouse
Concentration	1 mg/ml

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Menge: 0.1 mg

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Lieferung vsl. bis 12.02.2026

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