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NTRK3 Antibody (Phospho-Tyr516)

ArtNr OAAF00485
Hersteller AVIVA Systems Biology
Menge 100 ug
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB, IF, IHC, ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Citations McGregor L.M., Genomics 22:267-272(1994).
Shelton D.L., J. Neurosci. 15:477-491(1995.
Ichaso N., Oncogene 17:1871-1875(1998).
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias ETS related protein-neurotrophic receptor tyrosine kinase fusion protein;ETV6-NTRK3 fusion;gp145(trkC);GP145-TrkC;Neurotrophic tyrosine kinase receptor type 3;neurotrophic tyrosine kinase,receptor,type 3;NT-3 growth factor receptor;TRKC;TrkC tyrosine kinase;tyrosine kinase receptor C.
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot
Manufacturer - Category
Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Polyclonal Antibodies/Phospho Specific
Shipping Temperature
Wet Ice
Molecular Weight
94 kDa
Manufacturer - Application Additional Information
WB: 1:500~1:3000; IHC: 1:50~1:100; ELISA: 1:10000
Gene symbol
NTRK3
Gene Fullname
neurotrophic receptor tyrosine kinase 3
Product format
Liquid
Reconstitution and storage
-20°C
Description of target
Receptor tyrosine kinase involved in nervous system and probably heart development. Upon binding of its ligand NTF3/neurotrophin-3, NTRK3 autophosphorylates and activates different signaling pathways, including the phosphatidylinositol 3-kinase/AKT and the MAPK pathways, that control cell survival and differentiation.
Protein accession_num
NP_001012338.1
Protein name
NT-3 growth factor receptor
Clonality
Polyclonal
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen
The antiserum was produced against synthesized peptide derived from human Trk C around the phosphorylation site of Tyr516.
Dilution
The optimal working dilution should be determined by the end user.
Manufacturer - Specificity
Trk C (Phospho-Tyr516) antibody detects endogenous levels of Trk C only when phosphorylated at tyrosine 516.
Formulation
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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