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Gab2 Antibody (Phospho-Ser623)

ArtNr OAAF00549
Hersteller AVIVA Systems Biology
Menge 100 ug
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB, IF, IHC, ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Citations Nishida K., Blood 93:1809-1816(1999).
Nagase T., DNA Res. 5:31-39(1998).
Taylor T.D., Nature 440:497-500(2006).
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Grb2-associated binder 2;GRB2-associated-binding protein 2;growth factor receptor bound protein 2-associated protein 2;pp100.
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot
Manufacturer - Category
Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Polyclonal Antibodies/Phospho Specific, Root Catalog/Products/Primary Antibodies
Shipping Temperature
Wet Ice
Molecular Weight
74 kDa
Manufacturer - Application Additional Information
WB: 1:500~1:3000; IHC: 1:50~1:100; ELISA: 1:1000
Gene symbol
GAB2
Gene Fullname
GRB2 associated binding protein 2
Product format
Liquid
Reconstitution and storage
-20°C
Description of target
Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis.
Protein accession_num
NP_036428.1
Protein name
GRB2-associated-binding protein 2
Clonality
Polyclonal
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen
The antiserum was produced against synthesized peptide derived from human Gab2 around the phosphorylation site of Ser623.
Dilution
The optimal working dilution should be determined by the end user.
Manufacturer - Specificity
Gab2 (Phospho-Ser623) antibody detects endogenous levels of Gab2 only when phosphorylated at serine 623.
Formulation
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
lieferbar

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