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SPHK2 Antibody (Phospho-Thr614)

ArtNr OAAF00574
Hersteller AVIVA Systems Biology
Menge 100 ug
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB, IF, IHC, ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Citations Liu H., J. Biol. Chem. 275:19513-19520(2000).
Wiemann S., Genome Res. 11:422-435(2001).
Ota T., Nat. Genet. 36:40-45(2004).
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias SK 2;SK-2;sphingosine kinase 2;SPK 2;SPK-2.
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot
Manufacturer - Category
Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Polyclonal Antibodies/Phospho Specific, Root Catalog/Products/Primary Antibodies
Shipping Temperature
Wet Ice
Molecular Weight
69 kDa
Manufacturer - Application Additional Information
IHC: 1:50~1:100; ELISA: 1:5000
Gene symbol
SPHK2
Gene Fullname
sphingosine kinase 2
Product format
Liquid
Reconstitution and storage
-20°C
Description of target
Catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra- and extracellular functions. Also acts on D-erythro-dihydrosphingosine, D-erythro-sphingosine and L-threo-dihydrosphingosine. Binds phosphoinositides.
Protein accession_num
NP_001191088.1
Protein name
Sphingosine kinase 2
Clonality
Polyclonal
Purification
The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
Immunogen
The antiserum was produced against synthesized peptide derived from human SPHK2 around the phosphorylation site of Thr614.
Dilution
The optimal working dilution should be determined by the end user.
Manufacturer - Specificity
SPHK2 (Phospho-Thr614) antibody detects endogenous levels of SPHK2 only when phosphorylated at threonine 614.
Formulation
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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