BACE1 Antibody

ArtNr	OAAF00666
Hersteller	AVIVA Systems Biology
Menge	100 ug
Kategorie	Oncology Neuroscience Molecular Targets for Neuroscience Aging & Neurological Disorders Protein Aggregation, Clearance & Misfolding Antibodies By Cell Type Adenocarcinoma Immunohistochemistry ELISA Immunofluorescence Immunocytochemistry Primary Antibodies Immunostaining Immunochemistry
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	IF, IHC, ICC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Citations	Vassar R., Science 286:735-741(1999). Sinha S., Nature 402:537-540(1999). Yan R., Nature 402:533-537(1999)
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	APP beta-secretase;asp 2;ASP2;aspartyl protease 2;BACE;beta-secretase 1;beta-secretase 1 precursor variant 1;beta-site amyloid beta A4 precursor protein-cleaving enzyme;Beta-site amyloid precursor protein cleaving enzyme 1;beta-site APP cleaving enzyme 1;beta-site APP-cleaving enzyme;HSPC104;memapsin-2;membrane-associated aspartic protease 2;transmembrane aspartic proteinase Asp2.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	Enzyme-linked immunosorbent assay\|Immunocytochemistry\|Immunofluorescence\|Immunohistochemistry\|Immunohistochemistry-Paraffin
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	55 kDa
Manufacturer - Application Additional Information	IHC: 1:50~1:100; IF: 1:100~1:500; ELISA: 1:1000
Gene symbol	BACE1
Gene Fullname	beta-secretase 1
Product format	Liquid
Reconstitution and storage	-20°C
Description of target	Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
Protein accession_num	NP_001193978.1
Protein name	Beta-secretase 1
Clonality	Polyclonal
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen	The antiserum was produced against synthesized peptide derived from human BACE.
Dilution	The optimal working dilution should be determined by the end user.
Manufacturer - Specificity	BACE antibody detects endogenous levels of total BACE protein.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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OAAF00666-datasheet.pdf

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Menge: 100 ug

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Lieferung vsl. bis 29.01.2026

Express-Lieferung: 17 Tage sparen

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