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PPP2CA Antibody

ArtNr OAAF00825
Hersteller AVIVA Systems Biology
Menge 100 ug
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB, IF, IHC, ICC, ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Citations Wen Chen, Cancer Res., Sep 2005; 65: 8183 - 8192.
Kathy Bonness, Mol. Cancer Ther., Nov 2006; 5: 2727 - 2736.
Stefaan Wera, J. Biol. Chem., Sep 1995; 270: 21374.
Todd D. Prickett, J. Biol. Chem., Sep 2004; 279: 38912 - 38920.
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias NEDLBA;PP2A-alpha;PP2Ac;PP2CA;PP2Calpha;protein phosphatase 2,catalytic subunit,alpha isozyme;replication protein C;RP-C;serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform.
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Applications
Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot
Manufacturer - Category
Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature
Wet Ice
Molecular Weight
35 kDa
Manufacturer - Application Additional Information
WB: 1:500~1:3000; IHC: 1:50~1:100; IF: 1:100~1:500; ELISA: 1:5000
Gene symbol
PPP2CA
Gene Fullname
protein phosphatase 2 catalytic subunit alpha
Product format
Liquid
Reconstitution and storage
-20°C
Description of target
PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGO2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I (By similarity). Can dephosphorylate SV40 large T antigen and p53/TP53. Activates RAF1 by dephosphorylating it at 'Ser-259'.
Protein accession_num
NP_002706.1
Protein name
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
Clonality
Polyclonal
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen
The antiserum was produced against synthesized peptide derived from human PP2A-alpha.
Dilution
The optimal working dilution should be determined by the end user.
Manufacturer - Specificity
PP2A-alpha (Ab-307) antibody detects endogenous levels of total PP2A-alpha protein.
Formulation
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
lieferbar

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