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PTGES3 Antibody

ArtNr OAAF00847
Hersteller AVIVA Systems Biology
Menge 100 ug
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB, IF, IHC, ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Citations Johnson J.L., Mol. Cell. Biol. 14:1956-1963(1994).
The MGC Project Team; Genome Res. 14:2121-2127(2004).
Freeman B.C., Science 296:2232-2235(2002)
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias cPGES;cytosolic prostaglandin E synthase;cytosolic prostaglandin E2 synthase;Hsp90 co-chaperone;P23;progesterone receptor complex p23;prostaglandin E synthase 3;prostaglandin E synthase 3 (cytosolic);TEBP;telomerase-binding protein p23;unactive progesterone receptor,23 kD.
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot
Manufacturer - Category
Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature
Wet Ice
Molecular Weight
18 kDa
Manufacturer - Application Additional Information
WB: 1:500~1:3000; IHC: 1:50~1:100; ELISA: 1:1000
Gene symbol
PTGES3
Gene Fullname
prostaglandin E synthase 3
Product format
Liquid
Reconstitution and storage
-20°C
Description of target
Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2) (PubMed:10922363). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes (PubMed:11274138, PubMed:12077419). Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway (PubMed:24711448).
Protein accession_num
NP_006592.3
Protein name
Prostaglandin E synthase 3
Clonality
Polyclonal
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen
The antiserum was produced against synthesized peptide derived from human TEBP.
Dilution
The optimal working dilution should be determined by the end user.
Manufacturer - Specificity
TEBP (Ab-113) antibody detects endogenous levels of total TEBP protein.
Formulation
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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