PTPRC Antibody

ArtNr	OAAF00990
Hersteller	AVIVA Systems Biology
Menge	100 ug
Kategorie	Oncology Neuroscience Neural Lineage Markers Metabolism Diabetes Molecular Targets for Neuroscience Antibodies By Cell Type Carcinoma Hematology Leukemia Lymphoma Myeloma Flow Cytometry Immunohistochemistry Immunoprecipitation Western Blot ELISA Immunofluorescence Immunocytochemistry Primary Antibodies By Organ Heart & Blood Cancer Immunostaining Progenitor Markers Immunochemistry
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IF, IHC, ICC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Citations	K M Tchou-Wong. Mol. Cell. Biol., Jan 1992; 12: 394 - 401. Daniel W. McKenney. J. Biol. Chem., Oct 1995; 270: 24949. Simon X. Liang. Physiol Genomics, Oct 2005; 23: 172 - 181.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	B220;CD45;CD45 antigen;CD45R;GP180;LCA;L-CA;Leukocyte common antigen;LY5;protein tyrosine phosphatase,receptor type,c polypeptide;receptor-type tyrosine-protein phosphatase C;T200;T200 glycoprotein;T200 leukocyte common antigen.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	Enzyme-linked immunosorbent assay\|Immunocytochemistry\|Immunofluorescence\|Immunohistochemistry\|Immunohistochemistry-Paraffin\|Western blot
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	147 kDa
Manufacturer - Application Additional Information	IHC: 1:50~1:100; IF: 1:100~1:500; ELISA: 1:1000
Gene symbol	PTPRC
Gene Fullname	protein tyrosine phosphatase receptor type C
Product format	Liquid
Reconstitution and storage	-20°C
Description of target	Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity (By similarity).
Protein accession_num	NP_002829.3
Protein name	Receptor-type tyrosine-protein phosphatase C
Clonality	Polyclonal
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen	The antiserum was produced against synthesized peptide derived from human CD45.
Dilution	The optimal working dilution should be determined by the end user.
Manufacturer - Specificity	CD45 antibody detects endogenous levels of total CD45 protein.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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Menge: 100 ug

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Lieferung vsl. bis 13.11.2025

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