EIF4EBP1 Antibody

ArtNr	OAAF01015
Hersteller	AVIVA Systems Biology
Menge	100 ug
Kategorie	Oncology Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Regulation of Appetite Antibodies By Cell Type Hematology Leukemia Immunohistochemistry Western Blot ELISA Immunofluorescence Immunocytochemistry Endocrine Regulation of Lipid Metabolism Primary Antibodies Immunostaining Immunochemistry
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	IF, IHC, ICC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Citations	M. Gorre, Blood (ASH Annual Meeting Abstracts), Nov 2005; 106: 2772. Robert J. J. Biol. Chem., Jul 2007; 282: 21176 - 21186. Xiaoyan Zhou, Clin. Cancer Res., Oct 2004; 10: 6779 - 6788.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	4EBP1;4E-BP1;BP-1;eIF4E-binding protein 1;eukaryotic translation initiation factor 4E-binding protein 1;PHAS-I;phosphorylated heat- and acid-stable protein regulated by insulin 1.
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	Enzyme-linked immunosorbent assay\|Immunocytochemistry\|Immunofluorescence\|Immunohistochemistry\|Immunohistochemistry-Paraffin
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	12 kDa
Manufacturer - Application Additional Information	IHC: 1:50~1:100; IF: 1:100~1:500; ELISA: 1:1000
Gene symbol	EIF4EBP1
Gene Fullname	eukaryotic translation initiation factor 4E binding protein 1
Product format	Liquid
Reconstitution and storage	-20°C
Description of target	Repressor of translation initiation that regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. In contrast, hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to initiation of translation. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways.
Protein accession_num	NP_004086.1
Protein name	Eukaryotic translation initiation factor 4E-binding protein 1
Clonality	Polyclonal
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen	The antiserum was produced against synthesized peptide derived from human 4E-BP1.
Dilution	The optimal working dilution should be determined by the end user.
Manufacturer - Specificity	4E-BP1 antibody detects endogenous levels of total 4E-BP1 protein.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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OAAF01015-datasheet.pdf

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Menge: 100 ug

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Lieferung vsl. bis 13.11.2025

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